Cargando…

Gliovascular and cytokine interactions modulate brain endothelial barrier in vitro

The glio-vascular unit (G-unit) plays a prominent role in maintaining homeostasis of the blood-brain barrier (BBB) and disturbances in cells forming this unit may seriously dysregulate BBB. The direct and indirect effects of cytokines on cellular components of the BBB are not yet unclear. The presen...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chaitanya, Ganta V, Cromer, Walter E, Wells, Shannon R, Jennings, Merilyn H, Couraud, P Olivier, Romero, Ignacio A, Weksler, Babette, Erdreich-Epstein, Anat, Mathis, J Michael, Minagar, Alireza, Alexander, J Steven
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2011
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3248576/ https://www.ncbi.nlm.nih.gov/pubmed/22112345 http://dx.doi.org/10.1186/1742-2094-8-162

Ejemplares similares

The hCMEC/D3 cell line as a model of the human blood brain barrier
por: Weksler, Babette, et al.
Publicado: (2013)

Neuronal and astrocytic interactions modulate brain endothelial properties during metabolic stresses of in vitro cerebral ischemia
por: Chaitanya, Ganta Vijay, et al.
Publicado: (2014)

Evaluation of Soluble Junctional Adhesion Molecule-A as a Biomarker of Human Brain Endothelial Barrier Breakdown
por: Haarmann, Axel, et al.
Publicado: (2010)

Oxidative and pro-inflammatory impact of regular and denicotinized cigarettes on blood brain barrier endothelial cells: is smoking reduced or nicotine-free products really safe?
por: Naik, Pooja, et al.
Publicado: (2014)

A human-derived neurovascular unit in vitro model to study the effects of cellular cross-talk and soluble factors on barrier integrity
por: Barberio, Chiara, et al.
Publicado: (2022)

Inflammatory cytokines induce MAdCAM-1 in murine hepatic endothelial cells and mediate alpha-4 beta-7 integrin dependent lymphocyte endothelial adhesion In Vitro
por: Ando, Tomoaki, et al.
Publicado: (2007)

Could an endoneurial endothelial crosstalk between Wnt/β-catenin and Sonic Hedgehog pathways underlie the early disruption of the infraorbital blood–nerve barrier following chronic constriction injury?
por: Moreau, Nathan, et al.
Publicado: (2017)

Targeting gliovascular connexins prevents inflammatory blood-brain barrier leakage and astrogliosis
por: De Bock, Marijke, et al.
Publicado: (2022)

Venous endothelial injury in central nervous system diseases
por: Alexander, Jonathan S, et al.
Publicado: (2013)

Matrix metalloproteinase-9 activity and a downregulated Hedgehog pathway impair blood-brain barrier function in an in vitro model of CNS tuberculosis
por: Brilha, Sara, et al.
Publicado: (2017)

Author Correction: Matrix metalloproteinase-9 activity and a downregulated Hedgehog pathway impair blood-brain barrier function in an in vitro model of CNS tuberculosis
por: Brilha, Sara, et al.
Publicado: (2018)

Identification of Peptide Ligands for Targeting to the Blood-Brain Barrier
por: van Rooy, Inge, et al.
Publicado: (2010)

Transcellular Targeting of Fiber- and Hexon-Modified Adenovirus Vectors across the Brain Microvascular Endothelial Cells In Vitro
por: Laakkonen, Johanna P., et al.
Publicado: (2012)

Evaluation of gliovascular functions of Aqp4 readthrough isoforms
por: Mueller, Shayna M., et al.
Publicado: (2023)

The transport of nifurtimox, an anti-trypanosomal drug, in an in vitro model of the human blood–brain barrier: Evidence for involvement of breast cancer resistance protein
por: Watson, Christopher P., et al.
Publicado: (2012)

Expression and localization of claudins-3 and -12 in transformed human brain endothelium
por: Schrade, Anja, et al.
Publicado: (2012)

Microparticles in multiple sclerosis and clinically isolated syndrome: effect on endothelial barrier function
por: Marcos-Ramiro, Beatriz, et al.
Publicado: (2014)

Prolonged Morphine Exposure Induces Increased Firm Adhesion in an in Vitro Model of the Blood–Brain Barrier
por: Strazza, Marianne, et al.
Publicado: (2016)

Brain Endothelial Cells Release Apical and Basolateral Microparticles in Response to Inflammatory Cytokine Stimulation: Relevance to Neuroinflammatory Stress?
por: Yun, J. Winny, et al.
Publicado: (2019)

African-American inflammatory bowel disease in a Southern U.S. health center
por: Veluswamy, Hemanth, et al.
Publicado: (2010)

GLUT1 deficiency: Retinal detrimental effects of gliovascular modulation
por: Henry, Matt, et al.
Publicado: (2020)

Inflammatory response of endothelial cells to a human endogenous retrovirus associated with multiple sclerosis is mediated by TLR4
por: Duperray, Alain, et al.
Publicado: (2015)

Role of KCNMA1 gene in breast cancer invasion and metastasis to brain
por: Khaitan, Divya, et al.
Publicado: (2009)

Uptake and cytotoxicity of citrate-coated gold nanospheres: Comparative studies on human endothelial and epithelial cells
por: Freese, Christian, et al.
Publicado: (2012)

Translation in astrocyte distal processes sets molecular heterogeneity at the gliovascular interface
por: Boulay, Anne- Cécile, et al.
Publicado: (2017)

Seizures elevate gliovascular unit Ca(2+) and cause sustained vasoconstriction
por: Tran, Cam Ha T., et al.
Publicado: (2020)

Obesity-associated hyperleptinemia alters the gliovascular interface of the hypothalamus to promote hypertension
por: Gruber, Tim, et al.
Publicado: (2021)

Megalencephalic leukoencephalopathy with subcortical cysts is a developmental disorder of the gliovascular unit
por: Gilbert, Alice, et al.
Publicado: (2021)

Transcriptomic Profiling Reveals Discrete Poststroke Dementia Neuronal and Gliovascular Signatures
por: Waller, Rachel, et al.
Publicado: (2022)

The angiogenic gene profile of circulating endothelial progenitor cells from ischemic stroke patients
por: Navarro-Sobrino, Míriam, et al.
Publicado: (2013)

Transient Receptor Potential Vanilloid in the Brain Gliovascular Unit: Prospective Targets in Therapy
por: Luo, Huilong, et al.
Publicado: (2021)

CCL2 Disrupts the Adherens Junction: Implications for Neuroinflammation
por: Roberts, Toni K., et al.
Publicado: (2012)

Endotoxin-Induced Monocytic Microparticles Have Contrasting Effects on Endothelial Inflammatory Responses
por: Wen, Beryl, et al.
Publicado: (2014)

Editorial: Developmental therapeutics in pediatric neuro-oncology
por: Makimoto, Atsushi, et al.
Publicado: (2023)

Frontal white matter hyperintensities, clasmatodendrosis and gliovascular abnormalities in ageing and post-stroke dementia
por: Chen, Aiqing, et al.
Publicado: (2016)

Sex-Dependent Gliovascular Interface Abnormality in the Hippocampus following Postnatal Immune Activation in Mice
por: Ardalan, Maryam, et al.
Publicado: (2022)

Gliovascular alterations in sporadic and familial Alzheimer's disease: APOE3 Christchurch homozygote glioprotection
por: Henao‐Restrepo, Julián, et al.
Publicado: (2022)

A Multi-System Approach Assessing the Interaction of Anticonvulsants with P-gp
por: Dickens, David, et al.
Publicado: (2013)

Drug-Induced Trafficking of P-Glycoprotein in Human Brain Capillary Endothelial Cells as Demonstrated by Exposure to Mitomycin C
por: Noack, Andreas, et al.
Publicado: (2014)

Synthesis and in Vitro Evaluation of BBB Permeability, Tumor Cell Uptake, and Cytotoxicity of a Series of Carboranylporphyrin Conjugates
por: Bhupathiraju, N. V. S. Dinesh K., et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_8frivmb5u2b88inv2fi0v00ks5