Optical recording of action potentials in mammalian neurons using a microbial rhodopsin

Reliable optical detection of single action potentials in mammalian neurons has been one of the longest-standing challenges in neuroscience. Here we achieve this goal by using the endogenous fluorescence of a microbial rhodopsin protein, Archaerhodopsin 3 (Arch) from Halorubrum sodomense, expressed...

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Detalles Bibliográficos
Autores principales: Kralj, Joel M., Douglass, Adam D., Hochbaum, Daniel R., Maclaurin, Dougal, Cohen, Adam E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3248630/
https://www.ncbi.nlm.nih.gov/pubmed/22120467
http://dx.doi.org/10.1038/nmeth.1782

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3248630/
https://www.ncbi.nlm.nih.gov/pubmed/22120467
http://dx.doi.org/10.1038/nmeth.1782

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