Nicorandil prevents endothelial dysfunction due to antioxidative effects via normalisation of NADPH oxidase and nitric oxide synthase in streptozotocin diabetic rats

BACKGROUND: Nicorandil, an anti-angina agent, reportedly improves outcomes even in angina patients with diabetes. However, the precise mechanism underlying the beneficial effect of nicorandil on diabetic patients has not been examined. We investigated the protective effect of nicorandil on endotheli...

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Detalles Bibliográficos
Autores principales: Serizawa, Ken-ichi, Yogo, Kenji, Aizawa, Ken, Tashiro, Yoshihito, Ishizuka, Nobuhiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Original Investigation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3248842/
https://www.ncbi.nlm.nih.gov/pubmed/22107602
http://dx.doi.org/10.1186/1475-2840-10-105

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