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A novel substitution matrix fitted to the compositional bias in Mollicutes improves the prediction of homologous relationships
BACKGROUND: Substitution matrices are key parameters for the alignment of two protein sequences, and consequently for most comparative genomics studies. The composition of biological sequences can vary importantly between species and groups of species, and classical matrices such as those in the BLO...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3248887/ https://www.ncbi.nlm.nih.gov/pubmed/22115330 http://dx.doi.org/10.1186/1471-2105-12-457 |