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A novel substitution matrix fitted to the compositional bias in Mollicutes improves the prediction of homologous relationships

BACKGROUND: Substitution matrices are key parameters for the alignment of two protein sequences, and consequently for most comparative genomics studies. The composition of biological sequences can vary importantly between species and groups of species, and classical matrices such as those in the BLO...

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Detalles Bibliográficos
Autores principales: Lemaitre, Claire, Barré, Aurélien, Citti, Christine, Tardy, Florence, Thiaucourt, François, Sirand-Pugnet, Pascal, Thébault, Patricia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3248887/
https://www.ncbi.nlm.nih.gov/pubmed/22115330
http://dx.doi.org/10.1186/1471-2105-12-457