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Mid- to Long-term Results of Surgical Treatment of ASD in Patients over 60 Years Old

BACKGROUND: There is controversy about the benefit of surgical correction of an atrial septal defect (ASD) in patients over 60 years old. The purpose of this study was to determine whether surgical treatment is beneficial in those 60 years of age or older. MATERIALS AND METHODS: We reviewed the clin...

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Autores principales: Jeong, In-Seok, Ahn, Byoung-Hee, Kim, Soon-Jin, Oh, Sang-Gi, Oh, Bong-Suk, Kim, Sang-Hyung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Thoracic and Cardiovascular Surgery 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3249289/
https://www.ncbi.nlm.nih.gov/pubmed/22263140
http://dx.doi.org/10.5090/kjtcs.2011.44.2.137
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author Jeong, In-Seok
Ahn, Byoung-Hee
Kim, Soon-Jin
Oh, Sang-Gi
Oh, Bong-Suk
Kim, Sang-Hyung
author_facet Jeong, In-Seok
Ahn, Byoung-Hee
Kim, Soon-Jin
Oh, Sang-Gi
Oh, Bong-Suk
Kim, Sang-Hyung
author_sort Jeong, In-Seok
collection PubMed
description BACKGROUND: There is controversy about the benefit of surgical correction of an atrial septal defect (ASD) in patients over 60 years old. The purpose of this study was to determine whether surgical treatment is beneficial in those 60 years of age or older. MATERIALS AND METHODS: We reviewed the clinical course of 57 patients (mean age: 63.54±5.59 years) diagnosed with an isolated secundum ASD after the age of 60. The 24 patients (group A) who underwent surgical repair were compared with the 33 patients (group B) who were treated non-surgically. The mean follow-up period was 6.8±4.5 years. RESULTS: One operative death, 5 late deaths (20.8%) in group A, and 9 deaths (27.3%) in group B occurred in the study period. Symptomatic improvement was noted in 18 patients (75%) of group A after surgery. However 13 patients (39.4%) of group B showed symptomatic improvement during the follow-up period (p=0.012). The incidence of new atrial arrhythmia of the two groups was significantly different (16.7% vs 36.7%, p=0.038). The actuarial 10 year survival rate was 79% in group A and 73% in group B. CONCLUSION: Although surgical correction of ASD did not increase survival in patients over 60 years old, the surgical outcomes of ASD showed low operative mortality and resulted in symptomatic improvement in the majority of these patients. This study has shown the benefits of surgical closure of ASD even in advanced age in comparison to medical treatment.
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spelling pubmed-32492892012-01-19 Mid- to Long-term Results of Surgical Treatment of ASD in Patients over 60 Years Old Jeong, In-Seok Ahn, Byoung-Hee Kim, Soon-Jin Oh, Sang-Gi Oh, Bong-Suk Kim, Sang-Hyung Korean J Thorac Cardiovasc Surg Clinical Research BACKGROUND: There is controversy about the benefit of surgical correction of an atrial septal defect (ASD) in patients over 60 years old. The purpose of this study was to determine whether surgical treatment is beneficial in those 60 years of age or older. MATERIALS AND METHODS: We reviewed the clinical course of 57 patients (mean age: 63.54±5.59 years) diagnosed with an isolated secundum ASD after the age of 60. The 24 patients (group A) who underwent surgical repair were compared with the 33 patients (group B) who were treated non-surgically. The mean follow-up period was 6.8±4.5 years. RESULTS: One operative death, 5 late deaths (20.8%) in group A, and 9 deaths (27.3%) in group B occurred in the study period. Symptomatic improvement was noted in 18 patients (75%) of group A after surgery. However 13 patients (39.4%) of group B showed symptomatic improvement during the follow-up period (p=0.012). The incidence of new atrial arrhythmia of the two groups was significantly different (16.7% vs 36.7%, p=0.038). The actuarial 10 year survival rate was 79% in group A and 73% in group B. CONCLUSION: Although surgical correction of ASD did not increase survival in patients over 60 years old, the surgical outcomes of ASD showed low operative mortality and resulted in symptomatic improvement in the majority of these patients. This study has shown the benefits of surgical closure of ASD even in advanced age in comparison to medical treatment. Korean Society for Thoracic and Cardiovascular Surgery 2011-04 2011-04-14 /pmc/articles/PMC3249289/ /pubmed/22263140 http://dx.doi.org/10.5090/kjtcs.2011.44.2.137 Text en © The Korean Society for Thoracic and Cardiovascular Surgery. 2011. All right reserved. This is an open access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Clinical Research
Jeong, In-Seok
Ahn, Byoung-Hee
Kim, Soon-Jin
Oh, Sang-Gi
Oh, Bong-Suk
Kim, Sang-Hyung
Mid- to Long-term Results of Surgical Treatment of ASD in Patients over 60 Years Old
title Mid- to Long-term Results of Surgical Treatment of ASD in Patients over 60 Years Old
title_full Mid- to Long-term Results of Surgical Treatment of ASD in Patients over 60 Years Old
title_fullStr Mid- to Long-term Results of Surgical Treatment of ASD in Patients over 60 Years Old
title_full_unstemmed Mid- to Long-term Results of Surgical Treatment of ASD in Patients over 60 Years Old
title_short Mid- to Long-term Results of Surgical Treatment of ASD in Patients over 60 Years Old
title_sort mid- to long-term results of surgical treatment of asd in patients over 60 years old
topic Clinical Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3249289/
https://www.ncbi.nlm.nih.gov/pubmed/22263140
http://dx.doi.org/10.5090/kjtcs.2011.44.2.137
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