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Tumor Vascular Morphology Undergoes Dramatic Changes during Outgrowth of B16 Melanoma While Proangiogenic Gene Expression Remains Unchanged

In established tumors, angiogenic endothelial cells (ECs) coexist next to “quiescent” EC in matured vessels. We hypothesized that angio-gene expression of B16.F10 melanoma would differ depending on the growth stage. Unraveling the spatiotemporal nature thereof is essential for drug regimen design ai...

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Detalles Bibliográficos
Autores principales:	Langenkamp, Elise, vom Hagen, Franziska M., Zwiers, Peter J., Moorlag, Henk E., Schouten, Jan P., Hammes, Hans-Peter, Gouw, Annette S. H., Molema, Grietje
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	International Scholarly Research Network 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3249352/ https://www.ncbi.nlm.nih.gov/pubmed/22235379 http://dx.doi.org/10.5402/2011/409308

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