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Upregulation of DR3 expression in CD4(+) T cells promotes secretion of IL-17 in experimental autoimmune uveitis

PURPOSE: This study investigated the role of death receptor 3 (DR3) in experimental autoimmune uveitis (EAU). METHODS: EAU was induced in B10.RIII mice by subcutaneous injection of interphotoreceptor retinoid-binding protein (IRBP) 161–180 emulsified with complete Freund’s adjuvant and evaluated wit...

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Detalles Bibliográficos
Autor principal: Qin, Tingyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Vision 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3249436/
https://www.ncbi.nlm.nih.gov/pubmed/22219644