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Fuzzy oil drop model to interpret the structure of antifreeze proteins and their mutants

Mutations in proteins introduce structural changes and influence biological activity: the specific effects depend on the location of the mutation. The simple method proposed in the present paper is based on a two-step model of in silico protein folding. The structure of the first intermediate is ass...

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Detalles Bibliográficos
Autores principales: Banach, Mateusz, Prymula, Katarzyna, Jurkowski, Wiktor, Konieczny, Leszek, Roterman, Irena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer-Verlag 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3249532/
https://www.ncbi.nlm.nih.gov/pubmed/21523554
http://dx.doi.org/10.1007/s00894-011-1033-4