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Fuzzy oil drop model to interpret the structure of antifreeze proteins and their mutants
Mutations in proteins introduce structural changes and influence biological activity: the specific effects depend on the location of the mutation. The simple method proposed in the present paper is based on a two-step model of in silico protein folding. The structure of the first intermediate is ass...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer-Verlag
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3249532/ https://www.ncbi.nlm.nih.gov/pubmed/21523554 http://dx.doi.org/10.1007/s00894-011-1033-4 |