2-Hydroxylethyl methacrylate (HEMA), a tooth restoration component, exerts its genotoxic effects in human gingival fibroblasts trough methacrylic acid, an immediate product of its degradation

HEMA (2-hydroxyethyl methacrylate), a methacrylate commonly used in dentistry, was reported to induce genotoxic effects, but their mechanism is not fully understood. HEMA may be degraded by the oral cavity esterases or through mechanical stress following the chewing process. Methacrylic acid (MAA) i...

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Detalles Bibliográficos
Autores principales: Szczepanska, Joanna, Poplawski, Tomasz, Synowiec, Ewelina, Pawlowska, Elzbieta, Chojnacki, Cezary J., Chojnacki, Jan, Blasiak, Janusz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3249584/
https://www.ncbi.nlm.nih.gov/pubmed/21617943
http://dx.doi.org/10.1007/s11033-011-0895-y

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