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Formulation and Optimization of Mucoadhesive Nanodrug Delivery System of Acyclovir

Acyclovir is an antiviral drug used for the treatment of herpes simplex virus infections, with an oral bioavailability of only 10–20% [limiting absorption in gastrointestinal tract to duodenum and jejunum] and half-life of about 3 h, and is soluble only at acidic pH (pKa 2.27). Mucoadhesive polymeri...

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Detalles Bibliográficos
Autores principales:	Bhosale, UV, Kusum, Devi V, Jain, N
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Medknow Publications & Media Pvt Ltd 2011
Materias:	Pharmaceutics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3249739/ https://www.ncbi.nlm.nih.gov/pubmed/22224033 http://dx.doi.org/10.4103/0975-1483.90236

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