The effect of sodium and ultra filtration profile combination and cold dialysate on hypotension during hemodialysis and its symptoms

BACKGROUND: One of the most prevalent side effects of hemodialysis is intradialytic hypotension and its symptoms. Using sodium profiles 3 and ultra filtration profile 3 and cold dialysate are the ways to overcome this problem. Since none of these methods could control this complication lonely, this study was done to investigate the effect of combination of two methods on intradialytic hypotension. METHODS: This study was a cross over clinical trial in which 24 patients experienced intradialytic hypotension frequently, underwent three different methods of treatments during 9 successive hemodialysis sessions, group 1 used sodium profile 3 and ultra filtration profile 3, group 2 underwent hemodialysis with cold dialysate, and group 3received combination of both methods. Blood pressure was controlled before, during (3 times) and after hemodialysis. Data were analyzed via SPSS version 15, using x(2) and ANOVA test. RESULTS: Findings showed that although there was no significant difference considering intradialytic hypotension and its symptoms in two groups of sodium profile 3 and ultra filtration profile 3 and cold dialysate and the combination group (p > 0.05), but there was a significant difference considering the mean of blood pressure in three groups (p < 0.05). In combination group, drop of systolic and diastolic blood pressure was less than groups using each of methods. CONCLUSIONS: Concerning the decreased rate of hypotension using combination method, nurses can use this method to decrease intradialytic hypotension and help the patients undergo hemodialysis for enough time and improve their quality of life.