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Hepatoprotective effects of select water–soluble PARP inhibitors in a carbon tetrachloride model

BACKGROUND: Inhibitors of the nuclear enzyme poly (ADP-ribose) polymerase (PARP-1) have been demonstrated to attenuate pathophysiologic conditions associated with oxidative stress, specifically with carbon tetrachloride (CT)-induced hepatotoxicity. SETTINGS AND DESIGN: In this investigation, we eval...

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Detalles Bibliográficos
Autores principales:	McCluskey, James D, Sava, Dmytro, Harbison, Stephen C, Muro-Cacho, Carlos A, Giffe, Johnson T, Ping, Xu, Harbison, Raymond D
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Medknow Publications & Media Pvt Ltd 2011
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3249858/ https://www.ncbi.nlm.nih.gov/pubmed/22229131 http://dx.doi.org/10.4103/2229-5151.84788

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