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Light inactivation of water transport and protein–protein interactions of aquaporin–Killer Red chimeras

Aquaporins (AQPs) have a broad range of cellular and organ functions; however, nontoxic inhibitors of AQP water transport are not available. Here, we applied chromophore-assisted light inactivation (CALI) to inhibit the water permeability of AQP1, and of two AQP4 isoforms (M1 and M23), one of which...

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Detalles Bibliográficos
Autores principales: Baumgart, Florian, Rossi, Andrea, Verkman, A.S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3250104/
https://www.ncbi.nlm.nih.gov/pubmed/22200949
http://dx.doi.org/10.1085/jgp.201110712