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Light inactivation of water transport and protein–protein interactions of aquaporin–Killer Red chimeras
Aquaporins (AQPs) have a broad range of cellular and organ functions; however, nontoxic inhibitors of AQP water transport are not available. Here, we applied chromophore-assisted light inactivation (CALI) to inhibit the water permeability of AQP1, and of two AQP4 isoforms (M1 and M23), one of which...
Autores principales: | Baumgart, Florian, Rossi, Andrea, Verkman, A.S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3250104/ https://www.ncbi.nlm.nih.gov/pubmed/22200949 http://dx.doi.org/10.1085/jgp.201110712 |
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