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An extracellular domain of the accessory β1 subunit is required for modulating BK channel voltage sensor and gate

A family of tissue-specific auxiliary β subunits modulates large conductance voltage- and calcium-activated potassium (BK) channel gating properties to suit their diverse functions. Paradoxically, β subunits both promote BK channel activation through a stabilization of voltage sensor activation and...

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Detalles Bibliográficos
Autores principales: Gruslova, Aleksandra, Semenov, Iurii, Wang, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3250105/
https://www.ncbi.nlm.nih.gov/pubmed/22155735
http://dx.doi.org/10.1085/jgp.201110698