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An extracellular domain of the accessory β1 subunit is required for modulating BK channel voltage sensor and gate
A family of tissue-specific auxiliary β subunits modulates large conductance voltage- and calcium-activated potassium (BK) channel gating properties to suit their diverse functions. Paradoxically, β subunits both promote BK channel activation through a stabilization of voltage sensor activation and...
Autores principales: | Gruslova, Aleksandra, Semenov, Iurii, Wang, Bin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3250105/ https://www.ncbi.nlm.nih.gov/pubmed/22155735 http://dx.doi.org/10.1085/jgp.201110698 |
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