Toxic Epidermal Necrolysis with Ocular Involvement Following Vaccination for Hemorrhagic Fever with Renal Syndrome

We report a case of toxic epidermal necrolysis with ocular involvement following vaccination for hemorrhagic fever with renal syndrome. A healthy 20-year-old male soldier presented with confluent purpuric and erythematous dusky red macules evolving to flaccid blister and epidermal detachment on the...

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Autores principales: Hwang, Young Hoon, Kang, Myung Seung, Lim, Kyung O, Lee, Sang Mok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Yonsei University College of Medicine 2012
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3250336/
https://www.ncbi.nlm.nih.gov/pubmed/22187258
http://dx.doi.org/10.3349/ymj.2012.53.1.228
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author Hwang, Young Hoon
Kang, Myung Seung
Lim, Kyung O
Lee, Sang Mok
author_facet Hwang, Young Hoon
Kang, Myung Seung
Lim, Kyung O
Lee, Sang Mok
author_sort Hwang, Young Hoon
collection PubMed
description We report a case of toxic epidermal necrolysis with ocular involvement following vaccination for hemorrhagic fever with renal syndrome. A healthy 20-year-old male soldier presented with confluent purpuric and erythematous dusky red macules evolving to flaccid blister and epidermal detachment on the whole body with conjunctival injection. The patient had no antecedent medical or surgical conditions except for two doses of hemorrhagic fever with renal syndrome vaccination. With supportive care, skin lesions were improved. Ophthalmic examinations revealed conjunctival injection with epithelial defects in both eyes. Ocular complications were resolved after amniotic membrane transplantation. Toxic epidermal necrolysis may be considered as a possible complication of hemorrhagic fever with renal syndrome vaccination.
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spelling pubmed-32503362012-01-09 Toxic Epidermal Necrolysis with Ocular Involvement Following Vaccination for Hemorrhagic Fever with Renal Syndrome Hwang, Young Hoon Kang, Myung Seung Lim, Kyung O Lee, Sang Mok Yonsei Med J Case Report We report a case of toxic epidermal necrolysis with ocular involvement following vaccination for hemorrhagic fever with renal syndrome. A healthy 20-year-old male soldier presented with confluent purpuric and erythematous dusky red macules evolving to flaccid blister and epidermal detachment on the whole body with conjunctival injection. The patient had no antecedent medical or surgical conditions except for two doses of hemorrhagic fever with renal syndrome vaccination. With supportive care, skin lesions were improved. Ophthalmic examinations revealed conjunctival injection with epithelial defects in both eyes. Ocular complications were resolved after amniotic membrane transplantation. Toxic epidermal necrolysis may be considered as a possible complication of hemorrhagic fever with renal syndrome vaccination. Yonsei University College of Medicine 2012-01-01 2011-11-30 /pmc/articles/PMC3250336/ /pubmed/22187258 http://dx.doi.org/10.3349/ymj.2012.53.1.228 Text en © Copyright: Yonsei University College of Medicine 2012 http://creativecommons.org/licenses/by-nc/3.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Hwang, Young Hoon
Kang, Myung Seung
Lim, Kyung O
Lee, Sang Mok
Toxic Epidermal Necrolysis with Ocular Involvement Following Vaccination for Hemorrhagic Fever with Renal Syndrome
title Toxic Epidermal Necrolysis with Ocular Involvement Following Vaccination for Hemorrhagic Fever with Renal Syndrome
title_full Toxic Epidermal Necrolysis with Ocular Involvement Following Vaccination for Hemorrhagic Fever with Renal Syndrome
title_fullStr Toxic Epidermal Necrolysis with Ocular Involvement Following Vaccination for Hemorrhagic Fever with Renal Syndrome
title_full_unstemmed Toxic Epidermal Necrolysis with Ocular Involvement Following Vaccination for Hemorrhagic Fever with Renal Syndrome
title_short Toxic Epidermal Necrolysis with Ocular Involvement Following Vaccination for Hemorrhagic Fever with Renal Syndrome
title_sort toxic epidermal necrolysis with ocular involvement following vaccination for hemorrhagic fever with renal syndrome
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3250336/
https://www.ncbi.nlm.nih.gov/pubmed/22187258
http://dx.doi.org/10.3349/ymj.2012.53.1.228
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