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Bayesian Variable Selection in Searching for Additive and Dominant Effects in Genome-Wide Data
Although complex diseases and traits are thought to have multifactorial genetic basis, the common methods in genome-wide association analyses test each variant for association independent of the others. This computational simplification may lead to reduced power to identify variants with small effec...
Autores principales: | Peltola, Tomi, Marttinen, Pekka, Jula, Antti, Salomaa, Veikko, Perola, Markus, Vehtari, Aki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3250410/ https://www.ncbi.nlm.nih.gov/pubmed/22235263 http://dx.doi.org/10.1371/journal.pone.0029115 |
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