Cargando…

miR-122 Regulates p53/Akt Signalling and the Chemotherapy-Induced Apoptosis in Cutaneous T-Cell Lymphoma

Advanced cutaneous T-cell lymphoma (CTCL) is resistant to chemotherapy and presents a major area of medical need. In view of the known role of microRNAs (miRNAs) in the regulation of cellular signalling, we aimed to identify the functionally important miRNA species, which regulate apoptosis in CTCL....

Descripción completa

Detalles Bibliográficos
Autores principales:	Manfè, Valentina, Biskup, Edyta, Rosbjerg, Anne, Kamstrup, Maria, Skov, Anne Guldhammer, Lerche, Catharina Margrethe, Lauenborg, Britt Thyssing, Ødum, Niels, Gniadecki, Robert
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3250447/ https://www.ncbi.nlm.nih.gov/pubmed/22235305 http://dx.doi.org/10.1371/journal.pone.0029541

Ejemplares similares

cMyc/miR-125b-5p Signalling Determines Sensitivity to Bortezomib in Preclinical Model of Cutaneous T-Cell Lymphomas
por: Manfè, Valentina, et al.
Publicado: (2013)

Growth dynamics and cyclin expression in cutaneous T-cell lymphoma cell lines
por: Biskup, Edyta, et al.
Publicado: (2010)

Ubiquitin-specific protease 2 decreases p53-dependent apoptosis in cutaneous T-cell lymphoma
por: Wei, Tianling, et al.
Publicado: (2016)

miR-125b induces cellular senescence in malignant melanoma
por: Nyholm, Anne Marie, et al.
Publicado: (2014)

Malignant T cells express lymphotoxin α and drive endothelial activation in cutaneous T cell lymphoma
por: Lauenborg, Britt, et al.
Publicado: (2015)

Inhibition of H1N1 by Picochlorum sp. 122 via AKT and p53 signaling pathways
por: Chen, Danyang, et al.
Publicado: (2022)

Association of Common and Rare Genetic Variation in the 3‐Hydroxy‐3‐Methylglutaryl Coenzyme A Reductase Gene and Cataract Risk
por: Ghouse, Jonas, et al.
Publicado: (2022)

Understanding Cell Lines, Patient-Derived Xenograft and Genetically Engineered Mouse Models Used to Study Cutaneous T-Cell Lymphoma
por: Gill, Raman Preet Kaur, et al.
Publicado: (2022)

Photochemotherapy Induces Interferon Type III Expression via STING Pathway
por: Biskup, Edyta, et al.
Publicado: (2020)

miR-122 Regulates Tumorigenesis in Hepatocellular Carcinoma by Targeting AKT3
por: Nassirpour, Rounak, et al.
Publicado: (2013)

Treatment of Primary Cutaneous Anaplastic Large Cell Lymphoma with Superficial X-Rays
por: Jepsen, Malene E., et al.
Publicado: (2015)

Retraction: miR-122 Regulates Tumorigenesis in Hepatocellular Carcinoma by Targeting AKT3
Publicado: (2017)

Effect of Mir-122 on Human Cholangiocarcinoma Proliferation, Invasion, and Apoptosis Through P53 Expression
por: Wu, Cuiping, et al.
Publicado: (2016)

Keratinocyte Carcinoma and Photoprevention: The Protective Actions of Repurposed Pharmaceuticals, Phytochemicals and Vitamins
por: Pihl, Celina, et al.
Publicado: (2021)

Δ122p53, a mouse model of Δ133p53α, enhances the tumor-suppressor activities of an attenuated p53 mutant
por: Slatter, T L, et al.
Publicado: (2015)

Macular cutaneous amyloidosis treated with methyl aminolevulinate and daylight photodynamic therapy: A case report
por: Huang, Christina M, et al.
Publicado: (2019)

Detection of cutaneous malignant melanoma using RNA sampled by tape strips: A study protocol
por: Heerfordt, Ida M., et al.
Publicado: (2022)

A Skin Cancer Prophylaxis Study in Hairless Mice Using Methylene Blue, Riboflavin, and Methyl Aminolevulinate as Photosensitizing Agents in Photodynamic Therapy
por: Wulf, Hans Christian, et al.
Publicado: (2021)

Comparison of global DNA methylation analysis by whole genome bisulfite sequencing and the Infinium Mouse Methylation BeadChip using fresh and fresh-frozen mouse epidermis
por: Meyer, Olivia Strunge, et al.
Publicado: (2022)

Runs 117, 122 and 122': Tests of septum magnet for experiment R 201
por: Bonaudi, Franco
Publicado: (1971)

Chronic Obstructive Pulmonary Disease and Risk of Cutaneous T-cell Lymphoma: A Danish Population-based Cohort Study
por: SØRENSEN, Sissel B.T., et al.
Publicado: (2023)

122. Optimization of Antibiotic Time-Outs Within a Health System
por: Long, Ashley, et al.
Publicado: (2021)

Anti-PD-1 Therapy with Adjuvant Ablative Fractional Laser Improves Anti-Tumor Response in Basal Cell Carcinomas
por: Olesen, Uffe Høgh, et al.
Publicado: (2021)

Cellular Interactions and Inflammation in the Pathogenesis of Cutaneous T-Cell Lymphoma
por: Stolearenco, Veronica, et al.
Publicado: (2020)

Metformin decreases miR-122, miR-223 and miR-29a in women with polycystic ovary syndrome
por: Udesen, Pernille Bækgaard, et al.
Publicado: (2020)

Evasion Mechanisms Used by Pathogens to Escape the Lectin Complement Pathway
por: Rosbjerg, Anne, et al.
Publicado: (2017)

TP53 Gene Status Affects Survival in Advanced Mycosis Fungoides
por: Wooler, Gitte, et al.
Publicado: (2016)

Patterns of Gene Expression in Cutaneous T-Cell Lymphoma: Systematic Review of Transcriptomic Studies in Mycosis Fungoides
por: Motamedi, Melika, et al.
Publicado: (2021)

122nd LHCC Meeting
Publicado: (2015)

$^{120}$Cd and $^{122}$Cd
por: Scheidemann, Ø, et al.
Publicado: (1973)

Progress Report of the S122 experiment
por: CERN. Geneva. Electronic Experiments Committee
Publicado: (1973)

122nd SPSC Meeting
Publicado: (2016)

122 Peptide Inhibitors of HIV
por: Vahlne, Anders
Publicado: (2014)

Population Pharmacokinetics of CC-122
por: Cheng, Yiming, et al.
Publicado: (2021)

Health Tract, No. 122: Housewifery
Publicado: (1863)

Health Tract, No. 122: Housewifery
Publicado: (1865)

Is Cutaneous T-Cell Lymphoma Caused by Ultraviolet Radiation? A Comparison of UV Mutational Signatures in Malignant Melanoma and Mycosis Fungoides
por: Gniadecki, Robert, et al.
Publicado: (2023)

CPEB and two poly(A) polymerases control miR-122 stability and p53 mRNA translation
por: Burns, David, et al.
Publicado: (2011)

Malignant inflammation in cutaneous T‐cell lymphoma—a hostile takeover
por: Krejsgaard, Thorbjørn, et al.
Publicado: (2016)

Independent evolution of cutaneous lymphoma subclones in different microenvironments of the skin
por: Iyer, Aishwarya, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_1tu6fhm6mdqa67ofhlsmkhctic