MicroRNA-34a Modulates c-Myc Transcriptional Complexes to Suppress Malignancy in Human Prostate Cancer Cells

MicroRNA-34a (miR-34a), a potent mediator of tumor suppressor p53, has been reported to function as a tumor suppressor and miR-34a was found to be downregulated in prostate cancer tissues. We studied the functional effects of miR-34a on c-Myc transcriptional complexes in PC-3 prostate cancer cells....

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Detalles Bibliográficos
Autores principales: Yamamura, Soichiro, Saini, Sharanjot, Majid, Shahana, Hirata, Hiroshi, Ueno, Koji, Deng, Guoren, Dahiya, Rajvir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3250472/
https://www.ncbi.nlm.nih.gov/pubmed/22235332
http://dx.doi.org/10.1371/journal.pone.0029722

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3250472/
https://www.ncbi.nlm.nih.gov/pubmed/22235332
http://dx.doi.org/10.1371/journal.pone.0029722

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