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Alternative Splicing of RNA Triplets Is Often Regulated and Accelerates Proteome Evolution
Thousands of human genes contain introns ending in NAGNAG (N any nucleotide), where both NAGs can function as 3′ splice sites, yielding isoforms that differ by inclusion/exclusion of three bases. However, few models exist for how such splicing might be regulated, and some studies have concluded that...
Autores principales: | Bradley, Robert K., Merkin, Jason, Lambert, Nicole J., Burge, Christopher B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3250501/ https://www.ncbi.nlm.nih.gov/pubmed/22235189 http://dx.doi.org/10.1371/journal.pbio.1001229 |
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