Zscan4 transiently reactivates early embryonic genes during the generation of induced pluripotent stem cells

The generation of induced pluripotent stem cells (iPSCs) by the forced expression of defined transcription factors in somatic cells holds great promise for the future of regenerative medicine. However, the initial reprogramming mechanism is still poorly understood. Here we show that Zscan4, expresse...

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Detalles Bibliográficos
Autores principales: Hirata, Tetsuya, Amano, Tomokazu, Nakatake, Yuhki, Amano, Misa, Piao, Yulan, Hoang, Hien G., Ko, Minoru S. H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3250575/
https://www.ncbi.nlm.nih.gov/pubmed/22355722
http://dx.doi.org/10.1038/srep00208

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3250575/
https://www.ncbi.nlm.nih.gov/pubmed/22355722
http://dx.doi.org/10.1038/srep00208

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