Cargando…

Zscan4 transiently reactivates early embryonic genes during the generation of induced pluripotent stem cells

The generation of induced pluripotent stem cells (iPSCs) by the forced expression of defined transcription factors in somatic cells holds great promise for the future of regenerative medicine. However, the initial reprogramming mechanism is still poorly understood. Here we show that Zscan4, expresse...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hirata, Tetsuya, Amano, Tomokazu, Nakatake, Yuhki, Amano, Misa, Piao, Yulan, Hoang, Hien G., Ko, Minoru S. H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2012
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3250575/ https://www.ncbi.nlm.nih.gov/pubmed/22355722 http://dx.doi.org/10.1038/srep00208

Ejemplares similares

Zscan4 restores the developmental potency of embryonic stem cells
por: Amano, Tomokazu, et al.
Publicado: (2013)

Transient bursts of Zscan4 expression are accompanied by the rapid derepression of heterochromatin in mouse embryonic stem cells
por: Akiyama, Tomohiko, et al.
Publicado: (2015)

Repression of Global Protein Synthesis by Eif1a-Like Genes That Are Expressed Specifically in the Two-Cell Embryos and the Transient Zscan4-Positive State of Embryonic Stem Cells
por: Hung, Sandy S. C., et al.
Publicado: (2013)

Expression analysis of the endogenous Zscan4 locus and its coding proteins in mouse ES cells and preimplantation embryos
por: Ishiguro, Kei-ichiro, et al.
Publicado: (2016)

Generation and gene expression profiling of 48 transcription-factor-inducible mouse embryonic stem cell lines
por: Yamamizu, Kohei, et al.
Publicado: (2016)

Gene array analysis of neural crest cells identifies transcription factors necessary for direct conversion of embryonic fibroblasts into neural crest cells
por: Motohashi, Tsutomu, et al.
Publicado: (2016)

Systematic repression of transcription factors reveals limited patterns of gene expression changes in ES cells
por: Nishiyama, Akira, et al.
Publicado: (2013)

Zscan4 regulates telomere elongation and genomic stability in ES cells
por: Zalzman, Michal, et al.
Publicado: (2010)

Transient ectopic expression of the histone demethylase JMJD3 accelerates the differentiation of human pluripotent stem cells
por: Akiyama, Tomohiko, et al.
Publicado: (2016)

Correction of Down syndrome and Edwards syndrome aneuploidies in human cell cultures
por: Amano, Tomokazu, et al.
Publicado: (2015)

Topographic Cues Impact on Embryonic Stem Cell Zscan4-Metastate
por: Natale, Carlo F., et al.
Publicado: (2020)

Epigenetic Manipulation Facilitates the Generation of Skeletal Muscle Cells from Pluripotent Stem Cells
por: Akiyama, Tomohiko, et al.
Publicado: (2017)

Zscan4 Is Activated after Telomere Shortening in Mouse Embryonic Stem Cells
por: Nakai-Futatsugi, Yoko, et al.
Publicado: (2016)

Retinoic Acid Specifically Enhances Embryonic Stem Cell Metastate Marked by Zscan4
por: Tagliaferri, Daniela, et al.
Publicado: (2016)

Responsiveness of genes to manipulation of transcription factors in ES cells is associated with histone modifications and tissue specificity
por: Sharov, Alexei A, et al.
Publicado: (2011)

ZSCAN4 interacts with PARP1 to promote DNA repair in mouse embryonic stem cells
por: Tsai, Li-Kuang, et al.
Publicado: (2023)

Database for mRNA Half-Life of 19 977 Genes Obtained by DNA Microarray Analysis of Pluripotent and Differentiating Mouse Embryonic Stem Cells
por: Sharova, Lioudmila V., et al.
Publicado: (2009)

Zscan4 is expressed specifically during late meiotic prophase in both spermatogenesis and oogenesis
por: Ishiguro, Kei-ichiro, et al.
Publicado: (2016)

Identification of transcription factors that promote the differentiation of human pluripotent stem cells into lacrimal gland epithelium-like cells
por: Hirayama, Masatoshi, et al.
Publicado: (2017)

MERVL/Zscan4 Network Activation Results in Transient Genome-wide DNA Demethylation of mESCs
por: Eckersley-Maslin, Mélanie A., et al.
Publicado: (2016)

Pleiotropic Functions for Transcription Factor Zscan10
por: Kraus, Petra, et al.
Publicado: (2014)

Nr0b1 is a negative regulator of Zscan4c in mouse embryonic stem cells
por: Fujii, Setsuko, et al.
Publicado: (2015)

Correction: Pleiotropic Functions for Transcription Factor Zscan10
Publicado: (2015)

ZSCAN1 Autoantibodies Are Associated with Pediatric Paraneoplastic ROHHAD
por: Mandel‐Brehm, Caleigh, et al.
Publicado: (2022)

Using piggyBac transposon gene expression vectors to transfect Zscan5b gene into mouse pluripotent stem cells
por: Yamada, Mitsutoshi, et al.
Publicado: (2021)

Kinetics of drug selection systems in mouse embryonic stem cells
por: Nakatake, Yuhki, et al.
Publicado: (2013)

Improved Derivation Efficiency and Pluripotency of Stem Cells from the Refractory Inbred C57BL/6 Mouse Strain by Small Molecules
por: Lin, Chih-Jen, et al.
Publicado: (2014)

Controllable self-replicating RNA vaccine delivered intradermally elicits predominantly cellular immunity
por: Amano, Tomokazu, et al.
Publicado: (2023)

Generation and Characterization of Induced Pluripotent Stem Cells from Aid-Deficient Mice
por: Shimamoto, Ren, et al.
Publicado: (2014)

Establishment of a rapid and footprint-free protocol for differentiation of human embryonic stem cells into pancreatic endocrine cells with synthetic mRNAs encoding transcription factors
por: Ida, Hideomi, et al.
Publicado: (2018)

The necessity of ZSCAN4 for preimplantation development and gene expression of bovine embryos
por: TAKAHASHI, Kazuki, et al.
Publicado: (2019)

The Role of BDNF, YBX1, CENPF, ZSCAN4, TEAD4, GLIS1 and USF1 in the Activation of the Embryonic Genome in Bovine Embryos
por: Liu, Bingnan, et al.
Publicado: (2023)

Induction of human pluripotent stem cells into kidney tissues by synthetic mRNAs encoding transcription factors
por: Hiratsuka, Ken, et al.
Publicado: (2019)

Zscan4 Contributes to Telomere Maintenance in Telomerase-Deficient Late Generation Mouse ESCs and Human ALT Cancer Cells
por: Dan, Jiameng, et al.
Publicado: (2022)

ZSCAN4 facilitates chromatin remodeling and promotes the cancer stem cell phenotype
por: Portney, Benjamin A., et al.
Publicado: (2020)

Zscan4c activates endogenous retrovirus MERVL and cleavage embryo genes
por: Zhang, Weiyu, et al.
Publicado: (2019)

ZSCAN4 Regulates Zygotic Genome Activation and Telomere Elongation in Porcine Parthenogenetic Embryos
por: Li, Xiao-Han, et al.
Publicado: (2023)

The birth of embryonic pluripotency
por: Boroviak, Thorsten, et al.
Publicado: (2014)

Zinc Chloride Transiently Maintains Mouse Embryonic Stem Cell Pluripotency by Activating Stat3 Signaling
por: Hu, Jing, et al.
Publicado: (2016)

Direct conversion of mouse embryonic fibroblasts into functional keratinocytes through transient expression of pluripotency-related genes
por: Iacovides, Demetris, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_t00krvdhsebv2833o9bv1oqrgk