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CTL Escape and Viral Fitness in HIV/SIV Infection

Cytotoxic T lymphocyte (CTL) responses exert a suppressive effect on HIV and simian immunodeficiency virus (SIV) replication. Under the CTL pressure, viral CTL escape mutations are frequently selected with viral fitness costs. Viruses with such CTL escape mutations often need additional viral genome...

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Detalles Bibliográficos
Autores principales:	Seki, Sayuri, Matano, Tetsuro
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Research Foundation 2012
Materias:	Microbiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3250645/ https://www.ncbi.nlm.nih.gov/pubmed/22319514 http://dx.doi.org/10.3389/fmicb.2011.00267

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