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Pre-Clinical Assessment of (177)Lu-Labeled Trastuzumab Targeting HER2 for Treatment and Management of Cancer Patients with Disseminated Intraperitoneal Disease
Studies from this laboratory have demonstrated the potential of targeting HER2 for therapeutic and imaging applications with medically relevant radionuclides. To expand the repertoire of trastuzumab as a radioimmunoconjugate (RIC) vector, use of (177)Lu was investigated. The combination of a 6.7 d h...
Autores principales: | Ray, Geoffrey L., Baidoo, Kwamena E., Keller, Lanea M. M., Albert, Paul S., Brechbiel, Martin W., Milenic, Diane E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3250925/ https://www.ncbi.nlm.nih.gov/pubmed/22229017 http://dx.doi.org/10.3390/ph5010001 |
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