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A comparison of (111)In- or (64)Cu-DOTA-trastuzumab Fab fragments for imaging subcutaneous HER2-positive tumor xenografts in athymic mice using microSPECT/CT or microPET/CT

BACKGROUND: Our objective was to compare (111)In- or (64)Cu-DOTA-trastuzumab Fab fragments for imaging small or large s.c. tumor xenografts in athymic mice that display a wide range of human epidermal growth factor receptor-2 (HER2) expression using microSPECT/CT or microPET/CT. METHODS: Trastuzumab...

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Detalles Bibliográficos
Autores principales: Chan, Conrad, Scollard, Deborah A, McLarty, Kristin, Smith, Serena, Reilly, Raymond M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3250982/
https://www.ncbi.nlm.nih.gov/pubmed/22214307
http://dx.doi.org/10.1186/2191-219X-1-15