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Use of [(18)F]FDOPA-PET for in vivo evaluation of dopaminergic dysfunction in unilaterally 6-OHDA-lesioned rats
BACKGROUND: We evaluated the utility of L-3,4-dihydroxy-6-[(18)F]fluoro-phenylalanine ([(18)F]FDOPA) positron emission tomography (PET) as a method for assessing the severity of dopaminergic dysfunction in unilaterally 6-hydroxydopamine (6-OHDA)-lesioned rats by comparing it with quantitative bioche...
Autores principales: | Kyono, Kiyoshi, Takashima, Tadayuki, Katayama, Yumiko, Kawasaki, Toshiyuki, Zochi, Riyo, Gouda, Maki, Kuwahara, Yasuhiro, Takahashi, Kazuhiro, Wada, Yasuhiro, Onoe, Hirotaka, Watanabe, Yasuyoshi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3251329/ https://www.ncbi.nlm.nih.gov/pubmed/22214344 http://dx.doi.org/10.1186/2191-219X-1-25 |
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