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B7-H4 Treatment of T Cells Inhibits ERK, JNK, p38, and AKT Activation

B7-H4 is a newly identified B7 homolog that plays an important role in maintaining T-cell homeostasis by inhibiting T-cell proliferation and lymphokine-secretion. In this study, we investigated the signal transduction pathways inhibited by B7-H4 engagement in mouse T cells. We found that treatment o...

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Detalles Bibliográficos
Autores principales:	Wang, Xiaojie, Hao, Jianqiang, Metzger, Daniel L., Ao, Ziliang, Chen, Lieping, Ou, Dawei, Verchere, C. Bruce, Mui, Alice, Warnock, Garth L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3251556/ https://www.ncbi.nlm.nih.gov/pubmed/22238573 http://dx.doi.org/10.1371/journal.pone.0028232

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