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Depletion of B2 but Not B1a B Cells in BAFF Receptor-Deficient ApoE(−/−) Mice Attenuates Atherosclerosis by Potently Ameliorating Arterial Inflammation
We have recently identified conventional B2 cells as atherogenic and B1a cells as atheroprotective in hypercholesterolemic ApoE(−/−) mice. Here, we examined the development of atherosclerosis in BAFF-R deficient ApoE(−/−) mice because B2 cells but not B1a cells are selectively depleted in BAFF-R def...
Autores principales: | Kyaw, Tin, Tay, Christopher, Hosseini, Hamid, Kanellakis, Peter, Gadowski, Tahlia, MacKay, Fabeinne, Tipping, Peter, Bobik, Alex, Toh, Ban-Hock |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3251583/ https://www.ncbi.nlm.nih.gov/pubmed/22238605 http://dx.doi.org/10.1371/journal.pone.0029371 |
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