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Automated Reporter Quantification In Vivo: High-Throughput Screening Method for Reporter-Based Assays in Zebrafish
Reporter-based assays underlie many high-throughput screening (HTS) platforms, but most are limited to in vitro applications. Here, we report a simple whole-organism HTS method for quantifying changes in reporter intensity in individual zebrafish over time termed, Automated Reporter Quantification i...
Autores principales: | Walker, Steven L., Ariga, Junko, Mathias, Jonathan R., Coothankandaswamy, Veena, Xie, Xiayang, Distel, Martin, Köster, Reinhard W., Parsons, Michael J., Bhalla, Kapil N., Saxena, Meera T., Mumm, Jeff S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3251595/ https://www.ncbi.nlm.nih.gov/pubmed/22238673 http://dx.doi.org/10.1371/journal.pone.0029916 |
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