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Severe brain atrophy after long-term survival seen in siblings with familial amyotrophic lateral sclerosis and a mutation in the optineurin gene: a case series
INTRODUCTION: Previous studies have shown widespread multisystem degeneration in patients with sporadic amyotrophic lateral sclerosis who develop a total locked-in state and survive under mechanical ventilation for a prolonged period of time. However, the disease progressions reported in these studi...
Autores principales: | Ueno, Hiroki, Kobatake, Keitaro, Matsumoto, Masayasu, Morino, Hiroyuki, Maruyama, Hirofumi, Kawakami, Hideshi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3251630/ https://www.ncbi.nlm.nih.gov/pubmed/22152722 http://dx.doi.org/10.1186/1752-1947-5-573 |
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