Magnetic resonance imaging evaluation of Yukatan minipig brains for neurotherapy applications

Magnetic resonance imaging (MRI) of six Yukatan minipig brains was performed. The animals were placed in stereotaxic conditions currently used in experiments. To allow for correctpositioning of the animal in the MRI instrument, landmarks were previously traced on the snout of the pig. To avoid movem...

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Detalles Bibliográficos
Autores principales: Yun, Seung Pil, Kim, Dong Hyun, Ryu, Jung Min, Park, Jae Hong, Park, Su Shin, Jeon, Ji Hoon, Seo, Bit Na, Kim, Hyun-Jeong, Park, Jun-Gyu, Cho, Kyoung-Oh, Han, Ho Jae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Association for Laboratory Animal Science 2011
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3251761/
https://www.ncbi.nlm.nih.gov/pubmed/22232639
http://dx.doi.org/10.5625/lar.2011.27.4.309
Descripción
Sumario:Magnetic resonance imaging (MRI) of six Yukatan minipig brains was performed. The animals were placed in stereotaxic conditions currently used in experiments. To allow for correctpositioning of the animal in the MRI instrument, landmarks were previously traced on the snout of the pig. To avoid movements, animal were anesthetized. The animals were placed in a prone position in a Siemens Magnetom Avanto 1.5 System with a head coil. Axial T2-weighted and sagittal T1-weighted MRI images were obtained from each pig. Afterwards, the brains of the pigs were fixed and cut into axial sections. Histologic and MR images were compared. The usefulness of this technique is discussed.

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