Clinicopathological significance of indoleamine 2,3-dioxygenase 1 expression in colorectal cancer

BACKGROUND: Indoleamine 2,3-dioxygenase 1 (IDO1) is a tryptophan-catabolising enzyme that induces immune tolerance by modulating T-cell responses. Carcinomas may create an immunosuppressive state via IDO1 expression. Here we examined a possible contribution of IDO1 on this phenomenon and investigate...

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Detalles Bibliográficos
Autores principales: Ferdinande, L, Decaestecker, C, Verset, L, Mathieu, A, Moles Lopez, X, Negulescu, A-M, Van Maerken, T, Salmon, I, Cuvelier, C A, Demetter, P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Molecular Diagnostics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3251860/
https://www.ncbi.nlm.nih.gov/pubmed/22108515
http://dx.doi.org/10.1038/bjc.2011.513

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