Impact of anti-HER2 therapy on overall survival in HER2-overexpressing breast cancer patients with brain metastases

BACKGROUND: Trastuzumab-based therapy after diagnosis of brain metastases (BM) may improve survival due to prolonged systemic disease control. We investigated whether lapatinib may yield additional survival benefit. METHODS: Eighty patients with BM from HER2-positive breast cancer were identified. K...

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Detalles Bibliográficos
Autores principales: Bartsch, R, Berghoff, A, Pluschnig, U, Bago-Horvath, Z, Dubsky, P, Rottenfusser, A, DeVries, C, Rudas, M, Fitzal, F, Dieckmann, K, Mader, R M, Gnant, M, Zielinski, C C, Steger, G G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Clinical Study
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3251869/
https://www.ncbi.nlm.nih.gov/pubmed/22127284
http://dx.doi.org/10.1038/bjc.2011.531

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3251869/
https://www.ncbi.nlm.nih.gov/pubmed/22127284
http://dx.doi.org/10.1038/bjc.2011.531

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