Differential response of cancer cells to HDAC inhibitors trichostatin A and depsipeptide

BACKGROUND: Over the last decade, several drugs that inhibit class I and/or class II histone deacetylases (HDACs) have been identified, including trichostatin A, the cyclic depsipeptide FR901228 and the antibiotic apicidin. These compounds have had immediate application in cancer research because of...

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Detalles Bibliográficos
Autores principales: Chang, J, Varghese, D S, Gillam, M C, Peyton, M, Modi, B, Schiltz, R L, Girard, L, Martinez, E D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Translational Therapeutics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3251870/
https://www.ncbi.nlm.nih.gov/pubmed/22158273
http://dx.doi.org/10.1038/bjc.2011.532

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3251870/
https://www.ncbi.nlm.nih.gov/pubmed/22158273
http://dx.doi.org/10.1038/bjc.2011.532

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