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Contamination of Mesenchymal Stem-Cells with Fibroblasts Accelerates Neurodegeneration in an Experimental Model of Parkinson’s Disease

Pre-clinical studies have supported the use of mesenchymal stem cells (MSC) to treat highly prevalent neurodegenerative diseases such as Parkinson’s disease (PD) but preliminary trials have reported controversial results. In a rat model of PD induced by MPTP neurotoxin, we first observed a significa...

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Detalles Bibliográficos
Autores principales: Pereira, Marcia C. L., Secco, Mariane, Suzuki, Daniela E., Janjoppi, Luciana, Rodini, Carolina O., Torres, Layla B., Araújo, Bruno H. S., Cavalheiro, Esper A., Zatz, Mayana, Okamoto, Oswaldo Keith
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Humana Press Inc 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3252034/
https://www.ncbi.nlm.nih.gov/pubmed/21503590
http://dx.doi.org/10.1007/s12015-011-9256-4