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Effects of endotoxin exposure on childhood asthma risk are modified by a genetic polymorphism in ACAA1

BACKGROUND: Polymorphisms in the endotoxin-mediated TLR4 pathway genes have been associated with asthma and atopy. We aimed to examine how genetic polymorphisms in innate immunity pathways interact with endotoxin to influence asthma risk in children. METHODS: In a previous analysis of 372 children f...

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Detalles Bibliográficos
Autores principales:	Sordillo, Joanne E, Sharma, Sunita, Poon, Audrey, Lasky-Su, Jessica, Belanger, Kathleen, Milton, Donald K, Bracken, Michael B, Triche, Elizabeth W, Leaderer, Brian P, Gold, Diane R, Litonjua, Augusto A
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3252252/ https://www.ncbi.nlm.nih.gov/pubmed/22151743 http://dx.doi.org/10.1186/1471-2350-12-158

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