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A Mathematical Methodology for Determining the Temporal Order of Pathway Alterations Arising during Gliomagenesis

Human cancer is caused by the accumulation of genetic alterations in cells. Of special importance are changes that occur early during malignant transformation because they may result in oncogene addiction and thus represent promising targets for therapeutic intervention. We have previously described...

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Detalles Bibliográficos
Autores principales:	Cheng, Yu-Kang, Beroukhim, Rameen, Levine, Ross L., Mellinghoff, Ingo K., Holland, Eric C., Michor, Franziska
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3252265/ https://www.ncbi.nlm.nih.gov/pubmed/22241976 http://dx.doi.org/10.1371/journal.pcbi.1002337

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