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Joint Modelling of Confounding Factors and Prominent Genetic Regulators Provides Increased Accuracy in Genetical Genomics Studies

Expression quantitative trait loci (eQTL) studies are an integral tool to investigate the genetic component of gene expression variation. A major challenge in the analysis of such studies are hidden confounding factors, such as unobserved covariates or unknown subtle environmental perturbations. The...

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Detalles Bibliográficos
Autores principales:	Fusi, Nicoló, Stegle, Oliver, Lawrence, Neil D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3252274/ https://www.ncbi.nlm.nih.gov/pubmed/22241974 http://dx.doi.org/10.1371/journal.pcbi.1002330

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