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The Yeast Complex I Equivalent NADH Dehydrogenase Rescues pink1 Mutants
Pink1 is a mitochondrial kinase involved in Parkinson's disease, and loss of Pink1 function affects mitochondrial morphology via a pathway involving Parkin and components of the mitochondrial remodeling machinery. Pink1 loss also affects the enzymatic activity of isolated Complex I of the elect...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3252300/ https://www.ncbi.nlm.nih.gov/pubmed/22242018 http://dx.doi.org/10.1371/journal.pgen.1002456 |