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The Yeast Complex I Equivalent NADH Dehydrogenase Rescues pink1 Mutants

Pink1 is a mitochondrial kinase involved in Parkinson's disease, and loss of Pink1 function affects mitochondrial morphology via a pathway involving Parkin and components of the mitochondrial remodeling machinery. Pink1 loss also affects the enzymatic activity of isolated Complex I of the elect...

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Detalles Bibliográficos
Autores principales:	Vilain, Sven, Esposito, Giovanni, Haddad, Dominik, Schaap, Onno, Dobreva, Mariya P., Vos, Melissa, Van Meensel, Stefanie, Morais, Vanessa A., De Strooper, Bart, Verstreken, Patrik
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3252300/ https://www.ncbi.nlm.nih.gov/pubmed/22242018 http://dx.doi.org/10.1371/journal.pgen.1002456

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