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Mucin Depleted Foci, Colonic Preneoplastic Lesions Lacking Muc2, Show Up-Regulation of Tlr2 but Not Bacterial Infiltration

Mucin depleted foci (MDF) are precancerous lesions of the colon in carcinogen-treated rodents and humans at high risk. Since MDF show signs of inflammation we hypothesized that the defective mucous production would expose them to the risk of being penetrated by intestinal bacteria, which can be sens...

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Detalles Bibliográficos
Autores principales: Femia, Angelo Pietro, Swidsinski, Alexander, Dolara, Piero, Salvadori, Maddalena, Amedei, Amedeo, Caderni, Giovanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3252347/
https://www.ncbi.nlm.nih.gov/pubmed/22242189
http://dx.doi.org/10.1371/journal.pone.0029918

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