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Slit2/Robo4 Signaling Modulates HIV-1 gp120-Induced Lymphatic Hyperpermeability
Dissemination of HIV in the host involves transit of the virus and virus-infected cells across the lymphatic endothelium. HIV may alter lymphatic endothelial permeability to foster dissemination, but the mechanism is largely unexplored. Using a primary human lymphatic endothelial cell model, we foun...
Autores principales: | Zhang, Xuefeng, Yu, Jinlong, Kuzontkoski, Paula M., Zhu, Weiquan, Li, Dean Y., Groopman, Jerome E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3252370/ https://www.ncbi.nlm.nih.gov/pubmed/22241990 http://dx.doi.org/10.1371/journal.ppat.1002461 |
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