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Slit2/Robo4 Signaling Modulates HIV-1 gp120-Induced Lymphatic Hyperpermeability

Dissemination of HIV in the host involves transit of the virus and virus-infected cells across the lymphatic endothelium. HIV may alter lymphatic endothelial permeability to foster dissemination, but the mechanism is largely unexplored. Using a primary human lymphatic endothelial cell model, we foun...

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Detalles Bibliográficos
Autores principales: Zhang, Xuefeng, Yu, Jinlong, Kuzontkoski, Paula M., Zhu, Weiquan, Li, Dean Y., Groopman, Jerome E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3252370/
https://www.ncbi.nlm.nih.gov/pubmed/22241990
http://dx.doi.org/10.1371/journal.ppat.1002461

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