Cohesin acetyltransferase Esco2 is a cell viability factor and is required for cohesion in pericentric heterochromatin

Sister chromatid cohesion, mediated by cohesin and regulated by Sororin, is essential for chromosome segregation. In mammalian cells, cohesion establishment and Sororin recruitment to chromatin-bound cohesin depends on the acetyltransferases Esco1 and Esco2. Mutations in Esco2 cause Roberts syndrome...

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Detalles Bibliográficos
Autores principales: Whelan, Gabriela, Kreidl, Emanuel, Wutz, Gordana, Egner, Alexander, Peters, Jan-Michael, Eichele, Gregor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Molecular Biology Organization 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3252581/
https://www.ncbi.nlm.nih.gov/pubmed/22101327
http://dx.doi.org/10.1038/emboj.2011.381

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3252581/
https://www.ncbi.nlm.nih.gov/pubmed/22101327
http://dx.doi.org/10.1038/emboj.2011.381

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