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Effective transcutaneous immunization by antigen-loaded flexible liposome in vivo
BACKGROUND: Transcutaneous vaccines have received wide attention due to their easy-to-use, needle-free, noninvasive delivery. However, the novel barrier function of stratum corneum hinders the transport of antigen and adjuvant in transcutaneous immunization. Novel nanoscale delivery systems employin...
Autores principales: | Li, Ni, Peng, Li-Hua, Chen, Xi, Nakagawa, Shinsaku, Gao, Jian-Qing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3252672/ https://www.ncbi.nlm.nih.gov/pubmed/22228992 http://dx.doi.org/10.2147/IJN.S26152 |
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