Folate and vitamin B12 status in schizophrenic patients

BACKGROUND: This study aimed to determine red blood cell (RBC) and serum folate and vitamin B12 levels as well as their intake in schizophrenic patients. METHODS: The folate and cobalamin status of 60 schizophrenic patients (15-55 years) was compared to 60 matched healthy controls using Radio Isotop...

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Autores principales: Saedisomeolia, Ahmad, Djalali, Mahmoud, Moghadam, Ali Malekshahi, Ramezankhani, Ozra, Najmi, Laya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2011
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3252772/
https://www.ncbi.nlm.nih.gov/pubmed/22247731
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author Saedisomeolia, Ahmad
Djalali, Mahmoud
Moghadam, Ali Malekshahi
Ramezankhani, Ozra
Najmi, Laya
author_facet Saedisomeolia, Ahmad
Djalali, Mahmoud
Moghadam, Ali Malekshahi
Ramezankhani, Ozra
Najmi, Laya
author_sort Saedisomeolia, Ahmad
collection PubMed
description BACKGROUND: This study aimed to determine red blood cell (RBC) and serum folate and vitamin B12 levels as well as their intake in schizophrenic patients. METHODS: The folate and cobalamin status of 60 schizophrenic patients (15-55 years) was compared to 60 matched healthy controls using Radio Isotope Dilution Assay (RIDA). RESULTS: Serum and RBC folate in schizophrenic patients was significantly lower than the control group. Mean serum cobalamin levels in the schizophrenic group were higher than controls. CONCLUSIONS: This study showed that folate deficiency is common in schizophrenic patients; therefore, it is important to pay attention to folate levels in these patients.
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spelling pubmed-32527722012-01-13 Folate and vitamin B12 status in schizophrenic patients Saedisomeolia, Ahmad Djalali, Mahmoud Moghadam, Ali Malekshahi Ramezankhani, Ozra Najmi, Laya J Res Med Sci Short Communication BACKGROUND: This study aimed to determine red blood cell (RBC) and serum folate and vitamin B12 levels as well as their intake in schizophrenic patients. METHODS: The folate and cobalamin status of 60 schizophrenic patients (15-55 years) was compared to 60 matched healthy controls using Radio Isotope Dilution Assay (RIDA). RESULTS: Serum and RBC folate in schizophrenic patients was significantly lower than the control group. Mean serum cobalamin levels in the schizophrenic group were higher than controls. CONCLUSIONS: This study showed that folate deficiency is common in schizophrenic patients; therefore, it is important to pay attention to folate levels in these patients. Medknow Publications & Media Pvt Ltd 2011-03 /pmc/articles/PMC3252772/ /pubmed/22247731 Text en Copyright: © Journal of Research in Medical Sciences http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Short Communication
Saedisomeolia, Ahmad
Djalali, Mahmoud
Moghadam, Ali Malekshahi
Ramezankhani, Ozra
Najmi, Laya
Folate and vitamin B12 status in schizophrenic patients
title Folate and vitamin B12 status in schizophrenic patients
title_full Folate and vitamin B12 status in schizophrenic patients
title_fullStr Folate and vitamin B12 status in schizophrenic patients
title_full_unstemmed Folate and vitamin B12 status in schizophrenic patients
title_short Folate and vitamin B12 status in schizophrenic patients
title_sort folate and vitamin b12 status in schizophrenic patients
topic Short Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3252772/
https://www.ncbi.nlm.nih.gov/pubmed/22247731
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