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Differential Modulation of Thresholds for Intracranial Self-Stimulation by mGlu5 Positive and Negative Allosteric Modulators: Implications for Effects on Drug Self-Administration

Pharmacological manipulation of the type 5 metabotropic glutamate (mGlu5) receptor alters various addiction related behaviors such as drug self-administration and the extinction and reinstatement of drug-seeking behavior. However, the effects of pharmacological modulation of mGlu5 receptors on brain...

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Detalles Bibliográficos
Autores principales: Cleva, Richard M., Watterson, Lucas R., Johnson, Meagan A., Olive, M. Foster
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Research Foundation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3252814/
https://www.ncbi.nlm.nih.gov/pubmed/22232603
http://dx.doi.org/10.3389/fphar.2011.00093