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Many stimuli pull the necrotic trigger, an overview

The lab of Jürg Tschopp was the first to report on the crucial role of receptor-interacting protein kinase 1 (RIPK1) in caspase-independent cell death. Because of this pioneer finding, regulated necrosis and in particular RIPK1/RIPK3 kinase-mediated necrosis, referred to as necroptosis, has become a...

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Detalles Bibliográficos
Autores principales: Vanlangenakker, N, Vanden Berghe, T, Vandenabeele, P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3252835/
https://www.ncbi.nlm.nih.gov/pubmed/22075985
http://dx.doi.org/10.1038/cdd.2011.164