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Many stimuli pull the necrotic trigger, an overview
The lab of Jürg Tschopp was the first to report on the crucial role of receptor-interacting protein kinase 1 (RIPK1) in caspase-independent cell death. Because of this pioneer finding, regulated necrosis and in particular RIPK1/RIPK3 kinase-mediated necrosis, referred to as necroptosis, has become a...
Autores principales: | Vanlangenakker, N, Vanden Berghe, T, Vandenabeele, P |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3252835/ https://www.ncbi.nlm.nih.gov/pubmed/22075985 http://dx.doi.org/10.1038/cdd.2011.164 |
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