Directed aromatic functionalization in natural-product synthesis: Fredericamycin A, nothapodytine B, and topopyrones B and D

This is a review of our efforts toward the synthesis of a group of natural products that display noteworthy biological activity: Fredericamycin A, nothapodytine B, and topopyrones B and D. In each case, directed aromatic functionalization methodology greatly facilitated the assembly of the key molec...

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Detalles Bibliográficos
Autores principales: Turner, Charles Dylan, Ciufolini, Marco A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2011
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3252846/
https://www.ncbi.nlm.nih.gov/pubmed/22238520
http://dx.doi.org/10.3762/bjoc.7.171
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author Turner, Charles Dylan
Ciufolini, Marco A
author_facet Turner, Charles Dylan
Ciufolini, Marco A
author_sort Turner, Charles Dylan
collection PubMed
description This is a review of our efforts toward the synthesis of a group of natural products that display noteworthy biological activity: Fredericamycin A, nothapodytine B, and topopyrones B and D. In each case, directed aromatic functionalization methodology greatly facilitated the assembly of the key molecular subunits.
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spelling pubmed-32528462012-01-11 Directed aromatic functionalization in natural-product synthesis: Fredericamycin A, nothapodytine B, and topopyrones B and D Turner, Charles Dylan Ciufolini, Marco A Beilstein J Org Chem Review This is a review of our efforts toward the synthesis of a group of natural products that display noteworthy biological activity: Fredericamycin A, nothapodytine B, and topopyrones B and D. In each case, directed aromatic functionalization methodology greatly facilitated the assembly of the key molecular subunits. Beilstein-Institut 2011-10-28 /pmc/articles/PMC3252846/ /pubmed/22238520 http://dx.doi.org/10.3762/bjoc.7.171 Text en Copyright © 2011, Turner and Ciufolini https://creativecommons.org/licenses/by/2.0https://www.beilstein-journals.org/bjoc/termsThis is an Open Access article under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The license is subject to the Beilstein Journal of Organic Chemistry terms and conditions: (https://www.beilstein-journals.org/bjoc/terms)
spellingShingle Review
Turner, Charles Dylan
Ciufolini, Marco A
Directed aromatic functionalization in natural-product synthesis: Fredericamycin A, nothapodytine B, and topopyrones B and D
title Directed aromatic functionalization in natural-product synthesis: Fredericamycin A, nothapodytine B, and topopyrones B and D
title_full Directed aromatic functionalization in natural-product synthesis: Fredericamycin A, nothapodytine B, and topopyrones B and D
title_fullStr Directed aromatic functionalization in natural-product synthesis: Fredericamycin A, nothapodytine B, and topopyrones B and D
title_full_unstemmed Directed aromatic functionalization in natural-product synthesis: Fredericamycin A, nothapodytine B, and topopyrones B and D
title_short Directed aromatic functionalization in natural-product synthesis: Fredericamycin A, nothapodytine B, and topopyrones B and D
title_sort directed aromatic functionalization in natural-product synthesis: fredericamycin a, nothapodytine b, and topopyrones b and d
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3252846/
https://www.ncbi.nlm.nih.gov/pubmed/22238520
http://dx.doi.org/10.3762/bjoc.7.171
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